J Biomech Eng:用逆向有限元建模量化虹膜的力学性能

2018-03-24 cuiguizhong MedSci原创

美国阿克伦大学生物医学工程系Pant A近日在J Biomech Eng发表了一项重要工作,他们采用逆向有限元建模来确定体内虹膜的机械性质。

美国阿克伦大学生物医学工程系Pant A近日在J Biomech Eng发表了一项重要工作,他们采用逆向有限元建模来确定体内虹膜的机械性质。

量化虹膜的力学性质是很重要,因为它可以提供对青光眼病理生理学的认识。最近的体外研究表明,与正常人相比,虹膜的机械特性在青光眼眼中是不同的。尽管体外研究的重要性,但这种测量具有一定局限性,例如不能进行诊断和制定治疗策略。随着详细成像模式的出现,可以使用逆向有限元建模来确定体内虹膜的机械性质。

逆向有限元建模方法需要适当的目标函数来可靠地估计参数。以虹膜为例,在临床中需要进行诸如虹膜弦长和虹膜凹度等常规测量。在这项研究中,他们分别在存在和不存在临床测量误差的情况下,选择五种不同目标函数,评估虹膜生物特征,以确定逆向建模的适当标准。他们的结果表明,在没有实验测量误差的情况下,虹膜弦长和凹度的组合可以用作目标函数。然而,随着测量误差的增加,采用大量局部位移值的目标函数则更可靠。

原文出处:

Pant, A., S. Dorairaj, and R. Amini, Appropriate Objective Functions for Quantifying Iris Mechanical Properties Using Inverse Finite Element Modeling. J Biomech Eng, 2018.

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    2018-11-15 sunylz
  2. [GetPortalCommentsPageByObjectIdResponse(id=1917987, encodeId=9f02191e9870e, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Thu Nov 15 19:14:00 CST 2018, time=2018-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081458, encodeId=81cc208145853, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Dec 22 11:14:00 CST 2018, time=2018-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1754782, encodeId=2f771e54782ee, content=<a href='/topic/show?id=efff8856504' target=_blank style='color:#2F92EE;'>#虹膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88565, encryptionId=efff8856504, topicName=虹膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab9a36785616, createdName=LSJ123, createdTime=Sun Sep 23 18:14:00 CST 2018, time=2018-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299749, encodeId=5850299e491f, content=一起学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Mon Mar 26 07:08:45 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299401, encodeId=08ff299401ed, content=不错学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Mar 25 02:43:47 CST 2018, time=2018-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299364, encodeId=1614299364b3, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Mar 24 23:39:37 CST 2018, time=2018-03-24, status=1, ipAttribution=)]
    2018-12-22 spoonycyy
  3. [GetPortalCommentsPageByObjectIdResponse(id=1917987, encodeId=9f02191e9870e, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Thu Nov 15 19:14:00 CST 2018, time=2018-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081458, encodeId=81cc208145853, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Dec 22 11:14:00 CST 2018, time=2018-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1754782, encodeId=2f771e54782ee, content=<a href='/topic/show?id=efff8856504' target=_blank style='color:#2F92EE;'>#虹膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88565, encryptionId=efff8856504, topicName=虹膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab9a36785616, createdName=LSJ123, createdTime=Sun Sep 23 18:14:00 CST 2018, time=2018-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299749, encodeId=5850299e491f, content=一起学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Mon Mar 26 07:08:45 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299401, encodeId=08ff299401ed, content=不错学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Mar 25 02:43:47 CST 2018, time=2018-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299364, encodeId=1614299364b3, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Mar 24 23:39:37 CST 2018, time=2018-03-24, status=1, ipAttribution=)]
    2018-09-23 LSJ123
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    2018-03-26 wzb521zf

    一起学习学习

    0

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    2018-03-25 飛歌

    不错学习了很有用

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1917987, encodeId=9f02191e9870e, content=<a href='/topic/show?id=4f26341994' target=_blank style='color:#2F92EE;'>#Bio#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3419, encryptionId=4f26341994, topicName=Bio)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=12de429, createdName=sunylz, createdTime=Thu Nov 15 19:14:00 CST 2018, time=2018-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2081458, encodeId=81cc208145853, content=<a href='/topic/show?id=57406e8506' target=_blank style='color:#2F92EE;'>#Eng#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6785, encryptionId=57406e8506, topicName=Eng)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3516494, createdName=spoonycyy, createdTime=Sat Dec 22 11:14:00 CST 2018, time=2018-12-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1754782, encodeId=2f771e54782ee, content=<a href='/topic/show?id=efff8856504' target=_blank style='color:#2F92EE;'>#虹膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88565, encryptionId=efff8856504, topicName=虹膜)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab9a36785616, createdName=LSJ123, createdTime=Sun Sep 23 18:14:00 CST 2018, time=2018-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299749, encodeId=5850299e491f, content=一起学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Mon Mar 26 07:08:45 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299401, encodeId=08ff299401ed, content=不错学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Sun Mar 25 02:43:47 CST 2018, time=2018-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299364, encodeId=1614299364b3, content=谢谢分享学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Mar 24 23:39:37 CST 2018, time=2018-03-24, status=1, ipAttribution=)]
    2018-03-24 清风拂面

    谢谢分享学习

    0

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