Hypertension:妊娠并发症与将来发生高血压风险的关联

2017-03-13 luowenbo MedSci原创

妊娠能增加心血管病的风险,但妊娠与高血压或血压之间是否有关联仍然未知。该研究联系瑞典北部瑞典医学生育登记中心,获取韦斯特伯顿干预项目数据,在15896名年龄在40岁、有怀孕史、没有孕前高血压的女性中,分析其妊娠史中与高血压或血压有关的妊娠因素。妊娠因素包括:分娩、头胎年龄、先兆子癫、妊娠糖尿病、胎盘早剥、体重小于出生体重的第三百分位数的最短胎龄儿、死胎等。

妊娠并发症与将来发生高血压风险的关联

妊娠能增加心血管病的风险,但妊娠与高血压或血压之间是否有关联仍然未知。该研究联系瑞典北部瑞典医学生育登记中心,获取韦斯特伯顿干预项目数据,在15896名年龄在40岁、有怀孕史、没有孕前高血压的女性中,分析其妊娠史中与高血压或血压有关的妊娠因素。妊娠因素包括:分娩、头胎年龄、先兆子癫、妊娠糖尿病、胎盘早剥、体重小于出生体重的第三百分位数的最短胎龄儿、死胎等。

本研究中对高血压的定义为收缩压>=140mmHg、舒张压>=90mmHg或正在服用降压药。根据不同妊娠因素、不同生活方式和社会人口混杂因素建立多态模型。该研究中40岁的女性,1535名(9.6%)患有高血压。在多态模型中,分娩次数少、头胎年龄越小、先兆子癫、胎龄越小、胎盘早剥都与该研究中40岁的女性升高的收缩压与舒张压有关联。头胎年龄越年轻、出现先兆子癫、胎龄小于32周(与37周足月相比)和体重低于正常胎龄体重这四种因素分别都与高血压有关联。

该研究认为出现过上述妊娠因素的女性应该更早更频繁的进行血压监测,防控血压问题。

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    2017-10-31 丁鹏鹏
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    2017-08-19 feather89
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    2017-03-14 cuiyejia

    好文章,谢谢分享

    0

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