PNAS:肺结核患者福音——治疗型肺结核疫苗有望问世!

2017-11-25 佚名 medicalxpress

由南安普敦大学领导的科学家小组在研究工作中迈出了重要的一步,这一研究有望会研制带来有效的疫苗,来对付世界上最致命的传染病,肺结核。

由南安普敦大学领导的科学家小组在研究工作中迈出了重要的一步,这一研究有望会研制带来有效的疫苗,来对付世界上最致命的传染病,肺结核。

肺结核(TB)是最大的传染病杀手,据统计,全世界每年有170万人死于这种疾病。空气中的疾病对抗生素越来越耐药,尽管经过了20年的努力,还是没有研制出有效的疫苗来对抗这种致命疾病。

最近的研究集中在传统的人类T细胞,这是一种对抗感染所必需的白细胞,南安普顿大学和邦戈大学的研究人员,表明某些脂类,也就是脂肪物质的细胞结构可能引发了其他免疫应答。

发表在《美国国家科学院》杂志中的一项新研究中,研究小组发现,一组被称为分枝菌酸脂类的结核分枝杆菌细胞的主要组成部分是关键,决定了免疫反应。

来自南安普敦大学的研究人员表示:“这是对结核病患者的一大福音,我们已经证明,与结核分枝杆菌细胞壁相关的合成脂类是T细胞选择性靶向的关键,这一发现有望带来治疗肺结核的新方法,我们的研究结果还有助于疫苗发展,来预防和应对未来的结核病。”

邦戈大学的研究人员解释称:“这是有机化学和免疫学相结合的成果,可以大幅改进结核病的预防,这对于预防全世界肺结核疾病的流行做出了巨大的贡献。”

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    2018-05-19 drwjr
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    2018-02-28 1dd8c52fm63(暂无匿称)

    学习学习.继续关注

    0

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    2018-01-26 1dd8c52fm63(暂无匿称)

    了解了解.继续关注

    0

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    2017-11-26 杏林一叶

    拭目以待.

    0

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    2017-11-26 三生有幸9135

    学习一下谢谢分享

    0

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Chest:What?他汀还能降低肺结核风险

有研究表明,他汀类药物可能会降低感染疾病和感染相关死亡率的风险。2017年9月,发表在《Chest》的一项基于人群的研究调查了他汀与活动性肺结核(TB)之间的相关性。结果表明,他汀与较低的TB风险相关。

Nat Commun:科学家锁定肺结核的“罪魁祸首”,有望彻底“消灭”肺结核

科学家们解决了十年之久的谜团,这将带来肺结核的治疗方法,据统计,肺结核是全世界最致命的疾病之一,影响着全球20亿人口。

湖南桃江通报中学肺结核突发事件:近九成学生已复学或可复学

2017年8月19日,桃江县第四中学发生肺结核病突发公共卫生应急事件。疫情发生后,县委、县政府高度重视,第一时间启动县级突发公共卫生事件应急预案,并报告省、市疾控中心,立即开展治疗防控工作。

快讯!湖南通报桃江县第二起校园肺结核病疫情

湖南省卫计委20日下午通报湖南省桃江县另一起肺结核疫情。

湖南桃江县肺结核疫情:50名学生已达复学标准

桃江县政府还在新闻发布会现场承诺,及时准确发布疫情信息,并严肃查处此次结核病聚集性疫情处置工作中失职渎职行为。

马上评|桃江肺结核事件:追责不是终点,反思才刚开始

湖南桃江四中肺结核事件有了最新消息。桃江县委常委会决定:对县卫计局局长、教育局局长、疾控中心主任等人免职,建议县教育工委免去桃江四中党总支部书记、校长职务。县纪委、监察局将进一步依法依规开展调查,对在此次结核病聚集性疫情处置工作中存在的失职渎职行为予以严肃处理。事件真相逐渐揭开之后,追责总算启动了。但追责并不是我们的终极目的。这样一起重大公共卫生事件发生之后,我们更需要追问的是,从一名学生感染肺结