JAHA:急性心肌梗死住院早期和晚期心源性休克发病率和短期预后的趋势!

2017-06-08 xing.T MedSci原创

由此可见,院前和住院发发生的CS与较差的短期生存和住院死亡率相关,并且在那些院前CS患者中随着时间推移有所增加。主要集中在预防或治疗院前和晚期CS的干预措施是很有必要的,以改善急性心肌梗死后住院生存。

心源性休克(CS)是急性心肌梗死的严重并发症,其发病时间对其预后具有潜在影响。这种并发症的当前数据较为有限,尤其是以人群为基础的前瞻性数据。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究旨在描述CS发生率、住院死亡率和CS发生相关因素的十年长期趋势,在以下3种时空背景下:(1)到达医院之前的急性心肌梗死(院前CS);(2)住院24 小时内(早期CS);和住院后超过24小时(晚期CS)。

研究人群包括了5782名急性心肌梗死患者,这些受试者在2001年至2011年期间每两年在马萨诸塞州市中心的11家医院就诊。患者发生CS的整体比例为5.2%。院前CS患者的比例(1.6%)和晚期CS的比例(1.5%)随着时间的推移保持稳定,而早期CS患者的比例从2001年至2003年期间的2.2%下降到2009年至2011年期间的1.2%。院前CS患者的住院死亡率从2001年至2003年期间的38.9%增加到2009年至2011年期间的53.6%。而早期和晚期CS患者的住院死亡率随时间推移有所降低(分别从2001年至2003年期间的35.9%和64.7%降低至2009年至2011年期间的15.8%和39.1%。

由此可见,院前和住院发发生的CS与较差的短期生存和住院死亡率相关,并且在那些院前CS患者中随着时间推移有所增加。主要集中在预防或治疗院前和晚期CS的干预措施是很有必要的,以改善急性心肌梗死后住院生存。

原始出处:

Hoa L. Nguyen,et al. Ten‐Year (2001–2011) Trends in the Incidence Rates and Short‐Term Outcomes of Early Versus Late Onset Cardiogenic Shock After Hospitalization for Acute Myocardial Infarction.JAHA.2017.https://doi.org/10.1161/JAHA.117.005566

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    2017-06-10 zhaohui6731
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    2017-06-10 mhm295
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    2017-06-09 tanxingdoctor

    学习啦谢谢分享

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    2017-06-08 清风拂面

    谢谢,学习了

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