BMJ:普通开业医生进行细菌感染检测可减少抗生素的使用

2014-11-12 MedSci译 MedSci原创

Aabenhus等[1]发表于考克兰图书馆的一篇系统综述总结道:普通开业医生对病人进行细菌感染检测可减少不必要的抗生素的使用。BMJ对该系统综述进行了新闻报道。大部分有严重上呼吸道感染的病人是由于病毒感染引起的,服用抗生素并无作用。可快速检测是否有细菌或病毒感染的测试装备已经开发出来。目前普通开业医生可用的只有C反应蛋白测试。该测试只需3分钟即可完成,通过刺破病人手指获得一滴血用于测试其中的炎症生

Aabenhus等[1]发表于考克兰图书馆的一篇系统综述总结道:普通开业医生对病人进行细菌感染检测可减少不必要的抗生素的使用。BMJ对该系统综述进行了新闻报道。 大部分有严重上呼吸道感染的病人是由于病毒感染引起的,服用抗生素并无作用。可快速检测是否有细菌或病毒感染的测试装备已经开发出来。目前普通开业医生可用的只有C反应蛋白测试。该测试只需3分钟即可完成,通过刺破病人手指获得一滴血用于测试其中的炎症生物标记物—C反应蛋白。低水平的C反应蛋白可有效排除严重细菌感染的可能性,表明不需要使用抗生素。丹麦的研究者们综合分析了6项随机对照试验(3项独立的和3项集群的),包含3284名患者,大部分为成年人。结果发现在1685名接受过C反应蛋白测试的患者中631人被规定使用抗生素,而1599名未接受C反应蛋白测试的患者中785人被规定使用抗生素。与未接受测试组相比,接受测试组的抗生素使用低了22%,风险比为0.78(95%置信区间,0.66-0.92;I2=68%)。丹麦哥本哈根大学公共卫生学院首席研究员Rune Aabenhus说“这些研究结果表明:除了常规的检查,进行生物标记物测试可减少急性上呼

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1847628, encodeId=383c184e628b0, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Apr 11 15:29:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=12573, encodeId=c806125e30b, content=应该控制抗生素使用。, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160403/IMG5700F9EC14BED9452.jpg, createdBy=879d37419, createdName=cjyisheng, createdTime=Fri Nov 21 21:52:00 CST 2014, time=2014-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1280640, encodeId=a4751280640e7, content=<a href='/topic/show?id=beefe810798' target=_blank style='color:#2F92EE;'>#细菌感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78107, encryptionId=beefe810798, topicName=细菌感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, createdName=liuhuangbo, createdTime=Fri Nov 14 13:29:00 CST 2014, time=2014-11-14, status=1, ipAttribution=)]
    2015-04-11 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1847628, encodeId=383c184e628b0, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Apr 11 15:29:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=12573, encodeId=c806125e30b, content=应该控制抗生素使用。, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160403/IMG5700F9EC14BED9452.jpg, createdBy=879d37419, createdName=cjyisheng, createdTime=Fri Nov 21 21:52:00 CST 2014, time=2014-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1280640, encodeId=a4751280640e7, content=<a href='/topic/show?id=beefe810798' target=_blank style='color:#2F92EE;'>#细菌感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78107, encryptionId=beefe810798, topicName=细菌感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, createdName=liuhuangbo, createdTime=Fri Nov 14 13:29:00 CST 2014, time=2014-11-14, status=1, ipAttribution=)]
    2014-11-21 cjyisheng

    应该控制抗生素使用。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1847628, encodeId=383c184e628b0, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Sat Apr 11 15:29:00 CST 2015, time=2015-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=12573, encodeId=c806125e30b, content=应该控制抗生素使用。, beContent=null, objectType=article, channel=null, level=null, likeNumber=118, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160403/IMG5700F9EC14BED9452.jpg, createdBy=879d37419, createdName=cjyisheng, createdTime=Fri Nov 21 21:52:00 CST 2014, time=2014-11-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1280640, encodeId=a4751280640e7, content=<a href='/topic/show?id=beefe810798' target=_blank style='color:#2F92EE;'>#细菌感染#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78107, encryptionId=beefe810798, topicName=细菌感染)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, createdName=liuhuangbo, createdTime=Fri Nov 14 13:29:00 CST 2014, time=2014-11-14, status=1, ipAttribution=)]