Immunol Cell Biol:科学发话了,年轻人要多锻炼 ~

2016-01-07 佚名 生物谷

图片来源:www.thestatesman.com 人类的肠道之中包含有超过100万亿个微生物群体,近日,来自科罗拉多大学博尔德分校的研究人员通过研究发现,个体在年轻时(早年)锻炼或可帮助更好地改变机体的肠道微生物群落,同时还会在个体后期的生活中促进大脑的健康及机体的代谢,相关研究刊登于国际杂志Immunology and Cell Biology上。 该研究为研究人类早期发育从而优化改善

图片来源:www.thestatesman.com

人类的肠道之中包含有超过100万亿个微生物群体,近日,来自科罗拉多大学博尔德分校的研究人员通过研究发现,个体在年轻时(早年)锻炼或可帮助更好地改变机体的肠道微生物群落,同时还会在个体后期的生活中促进大脑的健康及机体的代谢,相关研究刊登于国际杂志Immunology and Cell Biology上。

该研究为研究人类早期发育从而优化改善人类健康的策略提供了一定的思路;研究者Monika Fleshner说道,锻炼可以影响机体健康的很多方面,包括代谢状况和精神状态,而当前人们才开始看到肠道微生物群落的可塑性;个体出生之后肠道微生物就寄居在肠道中,其对于机体免疫系统和多种神经功能的发挥都非常关键,而这些肠道微生物还会将500万基因加入到人类的整个基因“档案”中从而帮助改善并影响人类机体的多个生理学特性。

这种多样的微生物群落依然在成年后的机体中保持着一定的可塑性,而且容易被环境因子所影响,比如饮食和睡眠模式等,而研究者发现这些肠道微生物群落在个体年轻的时候尤其具有可塑性。研究者表示,相比静坐的小鼠及成体小鼠而言,自愿每天锻炼的幼年小鼠会产生一种较有益的微生物群落结构,包括肠道中益生菌菌种的增加等。

然而研究人员并没有指出具体的年龄范围适合肠道微生物菌群最有可能进行改变,但前期研究发现早期锻炼或许是最好的。健康强大的微生物群落可以帮助促进大脑的功能及健康,并且提供一种抗抑郁的效应,研究者Fleshner指出,人类的大脑会对来自肠道中的微生物信号产生反应,尽管其二者具体的交流方式目前并不清楚。未来研究者或对肠道的微生物生态系统进行大量研究来揭秘肠道微生物群落如何长期影响大脑的功能。

最后研究者计划寻找新型的方法来促进成年人机体肠道微生物群落的可塑性,从而帮助改善成年个体的健康,相关研究由NIH提供资助。

原始出处:

Agnieszka Mika1 and Monika Fleshner et al,Early life exercise may promote lasting brain and metabolic health through gut bacterial metabolites.Immunol Cell Biol.2015

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createdBy=446937890434, createdName=12498ebem31暂无昵称, createdTime=Sun Jun 26 01:20:00 CST 2016, time=2016-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1869280, encodeId=876a186928040, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Thu Nov 17 20:20:00 CST 2016, time=2016-11-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1959536, encodeId=c9971959536af, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Mon Jan 25 09:55:00 CST 2016, time=2016-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=57643, encodeId=d6cd5e643ed, content=年轻人锻炼更有意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Fri Jan 15 11:18:00 CST 2016, time=2016-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=55560, encodeId=039255560bc, content=科学, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24fb1657278, createdName=1dddecf7m78(暂无匿称), createdTime=Sun Jan 10 21:23:00 CST 2016, time=2016-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=54626, encodeId=272d5462673, content=好东西,值得分享,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=69b61619007, createdName=andruhn, createdTime=Fri Jan 08 15:36:00 CST 2016, time=2016-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=54459, encodeId=06ae54459d6, content=多锻炼, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151027/IMG562EB376ED6788263.jpg, createdBy=e6ea1659259, createdName=木醇阳, createdTime=Fri Jan 08 08:49:00 CST 2016, time=2016-01-08, status=1, ipAttribution=)]
    2016-10-11 维他命
  5. 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authenticateStatus=null, createdAvatar=, createdBy=24fb1657278, createdName=1dddecf7m78(暂无匿称), createdTime=Sun Jan 10 21:23:00 CST 2016, time=2016-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=54626, encodeId=272d5462673, content=好东西,值得分享,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=69b61619007, createdName=andruhn, createdTime=Fri Jan 08 15:36:00 CST 2016, time=2016-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=54459, encodeId=06ae54459d6, content=多锻炼, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151027/IMG562EB376ED6788263.jpg, createdBy=e6ea1659259, createdName=木醇阳, createdTime=Fri Jan 08 08:49:00 CST 2016, time=2016-01-08, status=1, ipAttribution=)]
    2016-10-08 sunylz
  6. 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authenticateStatus=null, createdAvatar=, createdBy=24fb1657278, createdName=1dddecf7m78(暂无匿称), createdTime=Sun Jan 10 21:23:00 CST 2016, time=2016-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=54626, encodeId=272d5462673, content=好东西,值得分享,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=69b61619007, createdName=andruhn, createdTime=Fri Jan 08 15:36:00 CST 2016, time=2016-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=54459, encodeId=06ae54459d6, content=多锻炼, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151027/IMG562EB376ED6788263.jpg, createdBy=e6ea1659259, createdName=木醇阳, createdTime=Fri Jan 08 08:49:00 CST 2016, time=2016-01-08, status=1, ipAttribution=)]
    2016-01-25 ssummer

    幼年时期经历对健康的长期影响

    0

  7. 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authenticateStatus=null, createdAvatar=, createdBy=24fb1657278, createdName=1dddecf7m78(暂无匿称), createdTime=Sun Jan 10 21:23:00 CST 2016, time=2016-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=54626, encodeId=272d5462673, content=好东西,值得分享,学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=69b61619007, createdName=andruhn, createdTime=Fri Jan 08 15:36:00 CST 2016, time=2016-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=54459, encodeId=06ae54459d6, content=多锻炼, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20151027/IMG562EB376ED6788263.jpg, createdBy=e6ea1659259, createdName=木醇阳, createdTime=Fri Jan 08 08:49:00 CST 2016, time=2016-01-08, status=1, ipAttribution=)]
    2016-01-15 医者仁心5538

    年轻人锻炼更有意义

    0

  8. 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createdTime=Fri Jan 08 08:49:00 CST 2016, time=2016-01-08, status=1, ipAttribution=)]
    2016-01-10 1dddecf7m78(暂无匿称)

    科学

    0

  9. 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    2016-01-08 andruhn

    好东西,值得分享,学习了!

    0

  10. 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createdTime=Fri Jan 08 08:49:00 CST 2016, time=2016-01-08, status=1, ipAttribution=)]
    2016-01-08 木醇阳

    多锻炼

    0

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