BMJ:消化不良的治疗管理策略

2019-12-13 MedSci 网络

研究认为,在消化不良的日常治疗,接受幽门螺杆菌检测及治疗是首要的干预手段,但研究倾向于将及时内镜检查作为治疗的首先策略

近日,研究人员开展系统综述及荟萃分析研究,考察治疗消化不良的有效策略。

本研究收集了截止2019年9月的相关研究,涉及18岁以上成年消化不良患者参与的随机对照研究,参与者接受幽门螺杆菌检测及内镜检查,幽门螺杆菌阳性人员进行根除治疗("检测和治疗"),阴性人群的治疗手段包括经验性酸抑制或基于症状的管理

15个随机对照试验,包括6162名参与者。数据采用随机效应模型进行汇总,根据P评分对策略进行分级。"测试和治疗"排在第一位(症状残留的相对危险度为0.89,P评分为0.79)、内镜检查排在第二位(0.90,P评分为0.71),与"测试和治疗"的重要性相当。但"检查和治疗"方案的治疗效率较低,且"测试和治疗"参与者接受内镜检查的意愿较低,而接受症状管理人群接受内镜检查的意愿较高。内镜检查获得的治疗满意度最高。所有患者上消化道癌的发生率都很低。

研究认为,在消化不良的日常治疗,接受幽门螺杆菌检测及治疗是首要的干预手段,但研究倾向于将及时内镜检查作为治疗的策略。

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    2022-03-27 屋顶瞄爱赏月

    学习了

    0

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    2020-02-25 gaoxiaoe
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    2020-07-01 gous

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