多西他赛+奈达铂二线治疗食管癌有效

2012-05-21 魏冬 医学论坛网

  日本一项研究表明,多西他赛联合奈达铂二线治疗复发或转移性食管癌有效,且患者耐受性良好。研究论文近期发表于《抗癌研究》(Anticancer Research)杂志。   该研究从2003年4月至2010年6月共纳入了18例患者,其中10例为转移性患者,8例为复发性患者。   第1、8和15天给予患者奈达铂(30 mg/m2)和多西他赛(30 mg/m2/日)治疗。  

  日本一项研究表明,多西他赛联合奈达铂二线治疗复发或转移性食管癌有效,且患者耐受性良好。研究论文近期发表于《抗癌研究》(Anticancer Research)杂志。

  该研究从2003年4月至2010年6月共纳入了18例患者,其中10例为转移性患者,8例为复发性患者。

  第1、8和15天给予患者奈达铂(30 mg/m2)和多西他赛(30 mg/m2/日)治疗。

  9例患者仅接受联合化疗,缓解率为22.2%(2/9)。

  另外9例接受联合化放疗,缓解率为55.5%(5/9)。

  结果显示,患者总体中位生存期为273天,接受联合化疗者为331天,接受联合化放疗者为244天。

  2年生存率为11.1%(1/9)。

  仅3例接受联合化放疗的患者出现了超过3级的白细胞增多。

      

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