Diabetes Care:关乎1型糖尿病青少年患者病情结局的因素

2017-04-28 MedSci MedSci原创

尽管1型糖尿病患者的生活存在许多挑战,但是许多青少年实现了“恢复的结局”:高度参与自我管理行为,如自我监测血糖(SMBG),良好的生活质量(QOL)和目标范围内血糖(HbA1c)。适应性糖尿病相关行为(即“优势”)与恢复的结果相关,但与恢复结果相关的风险和优势的组合尚不清楚。近期,一项发表在杂志Diabetes Care上的研究旨在心理和家庭风险因素的背景下调查糖尿病患者优势与恢复结局之间的关系。

尽管1型糖尿病患者的生活存在许多挑战,但是许多青少年实现了“恢复的结局”:高度参与自我管理行为,如自我监测血糖(SMBG),良好的生活质量(QOL)和目标范围内血糖(HbA1c)。适应性糖尿病相关行为(即“优势”)与恢复的结果相关,但与恢复结果相关的风险和优势的组合尚不清楚。

近期,一项发表在杂志Diabetes Care上的研究旨在心理和家庭风险因素的背景下调查糖尿病患者优势与恢复结局之间的关系。

共有471名澳大利亚1型糖尿病青少年(平均年龄15.7±1.9岁;糖尿病持续时间6.9±4.2岁; 62%女性; 53%使用胰岛素泵)完成了关于其糖尿病相关优势及风险因素(抑郁/焦虑症状,家庭冲突)和恢复结局(SMBG频率,一般的QOL,HbA1c)的全国横断面调查。

此项研究结果显示,更大的糖尿病优势与恢复的结果有显着相关性:更频繁的SMBG(r = 0.39),较低的HbA1c(r = -0.31)和较高的一般QOL(r = 0.50);风险降低的因素有:较少的抑郁(r = -0.45)和焦虑症状(r = -0.40)以及较少的冲突(r = 0.28)。在多变量回归分析中,糖尿病优势与超出重要风险因素的所有恢复的结果一致。

此项研究结果表明:在澳大利亚青少年的大样本中,即使存在着心理和家庭风险因素,糖尿病优势与关键的恢复性结果密切相关。鉴于与自我管理、HbA1c和总体生活质量的关联,监测和增强糖尿病优势可能会在青少年脆弱的发育期内促进疾病的恢复。

原始出处:
Hilliard ME, Hagger V, et al. Strengths, Risk Factors, and Resilient Outcomes in Adolescents With Type 1 Diabetes: Results From Diabetes MILES Youth-Australia. Diabetes Care. 2017 Apr 26. pii: dc162688. doi: 10.2337/dc16-2688.

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    2017-04-29 天涯183

    非常好的文章,学习了,很受益

    0

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