Photodiagnosis Photodyn Ther:抗菌光动力疗法可用于治疗种植体周围黏膜炎,但是骨再生的效果有限

2022-05-29 sunshine MedSci原创

未经治疗的种植体周围炎的最终结果是骨结合的丧失或种植体的丧失/失败。成功治疗的最终目标是永久消除种植体周围软组织炎症,并实现种植体周围的骨再生。

未经治疗的种植体周围炎的最终结果是骨结合的丧失或种植体的丧失/失败。成功治疗的最终目标是永久消除种植体周围软组织炎症,并实现种植体周围的骨再生。抗菌光动力疗法(aPDT)是常用的种植体周围炎的辅助疗法,旨在种植体表面去污,促进种植体周围的骨再生。然而,关于其确切疗效目前还没有达成共识。近日,发表于Photodiagnosis Photodyn Ther的一项随机对照试验评估了多个疗程的抗菌光动力疗法(aPDT)对种植体周围炎植体周围骨再生的影响。

研究纳入了种植体周围炎的患者。在治疗上,患者被随机分为4组:(a) 第一组:单纯机械清创(MD);(b) 第二组:在基线上进行MD,然后进行一次辅助PDT;(c) 第三组:在基线上进行MD,然后在基线和3个月的随访中进行aPDT;和第四组:在基线上进行MD,然后在基线和3、6个月的随访中使用aPDT。收集人口统计学数据,并在基线和9个月后评估种植体周围的临床(菌斑指数[PI]、牙龈指数[GI]和探诊深度[PD])和影像学(牙槽骨丧失[CBL])参数。

 

结果,分别各有22名种植体周围炎患者被纳入-I、-II、-III和-IV组。I、-II、-III和-IV组的平均年龄分别为59.2±5.3、60.5±2.8、59.6±3.1和58.7±0.8岁。分析结果显示,与I组相比,所有组别在9个月的随访中,PI(P<0.01)、GI(P<0.01)和PD(P<0.01)都有明显的下降。在9个月的随访中,第二组、第三组和第四组的PI、GI和PD没有明显差异。所有组别在基线和随访9个月时,CBL没有统计学上的显著差异。

综上所述,该研究结果表明,使用aPDT作为种植体周围炎的辅助治疗手段可以减少种植体周围粘膜炎的严重程度,但不会促进种植体周围的骨再生。

 

原始出处:

 

Shatha Subhi ALHarthi, et al., Effect of multiple sessions of photodynamic therapy on bone regeneration around dental implants among patients with peri‑implantitis. Photodiagnosis Photodyn Ther. 2022 Mar;37:102612. doi: 10.1016/j.pdpdt.2021.102612.  

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    2022-11-10 liuxiaona
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  4. 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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/TnzXXl41yf6V8fHrDb5JdtxOgpaY6vplUhHtL8BzDh1xMtcap9H1IOlE8umxPGovhIuVkeGTY26eNUFCFaOheQ/132, createdBy=29702500197, createdName=ms6279672939590805, createdTime=Wed May 11 13:04:46 CST 2022, time=2022-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472221, encodeId=055914e2221e9, content=<a href='/topic/show?id=d068101610b9' target=_blank style='color:#2F92EE;'>#骨再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101610, encryptionId=d068101610b9, topicName=骨再生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a4cf7208806, createdName=lsj630, createdTime=Wed May 11 13:04:46 CST 2022, time=2022-05-11, status=1, ipAttribution=)]
    2023-04-21 huangdf
  5. 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  6. 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createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/TnzXXl41yf6V8fHrDb5JdtxOgpaY6vplUhHtL8BzDh1xMtcap9H1IOlE8umxPGovhIuVkeGTY26eNUFCFaOheQ/132, createdBy=29702500197, createdName=ms6279672939590805, createdTime=Wed May 11 13:04:46 CST 2022, time=2022-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1472221, encodeId=055914e2221e9, content=<a href='/topic/show?id=d068101610b9' target=_blank style='color:#2F92EE;'>#骨再生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101610, encryptionId=d068101610b9, topicName=骨再生)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a4cf7208806, createdName=lsj630, createdTime=Wed May 11 13:04:46 CST 2022, time=2022-05-11, status=1, ipAttribution=)]
    2022-05-29 杨海东

    坚持学习

    0

  7. 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    2022-05-11 lsj630

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