BOA:揭秘饮食、肠道微生物组和结直肠癌发生之间的关联

2016-12-13 佚名 生物谷

最近对动物模型的研究证据表明,特殊类型的肠道细菌在结直肠癌的发病过程中扮演着重要角色,如果肠道中微生物菌群失衡会诱发机体患结直肠癌的话,那么基于饮食的治疗性干预措施或许就能够通过改善机体肠道微生物组的组成来降低个体的患癌风险。近日,来自德国慕尼黑理工大学的研究人员在国际杂志BioResearch Open Access上发表的一篇题为“Role of the Microbiota in Color

最近对动物模型的研究证据表明,特殊类型的肠道细菌在结直肠癌的发病过程中扮演着重要角色,如果肠道中微生物菌群失衡会诱发机体患结直肠癌的话,那么基于饮食的治疗性干预措施或许就能够通过改善机体肠道微生物组的组成来降低个体的患癌风险。

近日,来自德国慕尼黑理工大学的研究人员在国际杂志BioResearch Open Access上发表的一篇题为“Role of the Microbiota in Colorectal Cancer: Updates on Microbial Associations and Therapeutic Implications”的研究报告就阐明了饮食、肠道微生物组和结直肠癌之间的关联。

文章中,研究者Olivia Coleman和Tiago Nunes就讨论了肠道微生物群落和机体结直肠癌发育及进展之间的关联,以及二者之间关联性的重要性和意义,当然这对于研究者们开发新型干预措施来基于机体肠道微生物组降低个体患癌风险也提供了新的见解和思路。研究者强调了益生菌和益生元的保护效应,他们指出,益生菌和益生元能够通过调节机体肠道微生物组的平衡和功能,来扩大产乳酸细菌的水平,从而达到抵御结直肠癌的风险。

最后杂志编辑Jane Taylor说道,这篇综述文章为我们很好地解析了机体肠道微生物群落和结直肠癌发生之间的关联,当然文章中研究人员也提出了潜在的治疗方法和干预性措施,这对于有效利用机体肠道微生物群落来开发相应的干预措施降低结直肠癌的发病风险提供了一定的理论依据和研究基础。

原始出处:

Coleman OI1, Nunes T1.Role of the Microbiota in Colorectal Cancer: Updates on Microbial Associations and Therapeutic Implications.Biores Open Access. 2016 Oct 1

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    2016-12-26 1e10c84am36(暂无匿称)

    文章好好

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