Nanotechnology：新型介孔二氧化硅/还原氧化石墨烯纳米片可较好的发挥抗菌作用

2018-05-05 MedSci MedSci原创

细菌耐药性已成为一个全球性的健康问题，使得常规抗生素的效果变差。因此，迫切需要探索新型抗菌材料并制定有效的治疗策略来克服抗生素的耐药性。本研究中，研究人员通过简便的方法成功合成了银饰三明治状介孔二氧化硅/还原氧化石墨烯纳米片（rGO/MSN/Ag）作为新型抗菌材料。rGO和Ag纳米颗粒可在反应体系中还原而不添加任何其他还原剂。此外，由于银纳米粒子的改性，rGO/MSN/Ag具有较高的光热转化能力。

细菌耐药性已成为一个全球性的健康问题，使得常规抗生素的效果变差。因此，迫切需要探索新型抗菌材料并制定有效的治疗策略来克服抗生素的耐药性。本研究中，研究人员通过简便的方法成功合成了银饰三明治状介孔二氧化硅/还原氧化石墨烯纳米片（rGO/MSN/Ag）作为新型抗菌材料。

rGO和Ag纳米颗粒可在反应体系中还原而不添加任何其他还原剂。此外，由于银纳米粒子的改性，rGO/MSN/Ag具有较高的光热转化能力。

在较低剂量下，rGO/MSN/Ag对恶臭假单胞菌、大肠杆菌和红球菌具有优异的抗菌活性，最小抑制浓度（MIC）证实了此点。使用808 nm激光照射高浓度的大肠杆菌，近红外辐射诱导光热效应明显提高了抗菌效果。

此外，选用肝细胞LO2用于细胞毒性评估，结果显示，rGO/MSN/Ag具有低毒性，且在抗菌剂量下未发现其存在细胞毒性。

综上所述，该研究结果表明，rGO/MSN/Ag纳米片具有低成本和高抗菌活性的优点，或可成为一种有前景的抗菌剂。

原始出处：

Liu R, Wang X, et al., Enhanced antibacterial activity of silver-decorated sandwich-like mesoporous silica/reduced graphene oxide nanosheets through photothermal effect. Nanotechnology. 2018 Mar 9;29(10):105704. doi: 10.1088/1361-6528/aaa624.

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2019-03-02 luckyshitiancai_42705692

#介孔#

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2018-07-22 fzwish20000

#Technology#

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2018-07-23 yangjxjc

#石墨烯#

0 0
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2019-04-10 ms7899726347904398

#化石#

23 0
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2018-08-20 shock_melon

#TEC#

24 0
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2019-01-11 guojianrong

#二氧化硅#

45 0
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2018-05-07 ms7899726347904398

#抗菌#

23 0
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2018-05-05 虈亣靌

学习了.谢谢作者分享!

54 0

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Nanotechnology：新型介孔二氧化硅/还原氧化石墨烯纳米片可较好的发挥抗菌作用

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