Lancet 子刊:25岁以下人群的糖尿病死亡率及其趋势——2019年全球疾病负担研究的分析

2022-02-11 MedSci原创 MedSci原创

糖尿病的诊断和治疗不足可能是这些早期死亡的主要原因,这突出表明迫切需要提供更好的胰岛素和基础糖尿病教育和护理。

如果有正确的医疗保健和服务,1型糖尿病在很大程度上是可以预防的死因。本研究旨在利用2019年全球疾病、伤害和风险因素负担研究(GBD)的数据,评估全球25岁以下人群的糖尿病死亡率及其趋势。

研究者使用2019年GBD估计值来计算1990年和2019年25岁以下的国际糖尿病死亡率。死亡原因的数据来源来自1990年至2019年的生命登记系统、死因推断和其他监测系统。使用GBD死因集合模型估计了每个地点的死亡率,分析了每10万人年龄标准化死亡率与社会人口指数(SDI)和全民健康覆盖(UHC)的关系,并描述了SDI五分位内的变异性,给出了95%不确定区间的估计值。

2019年,全球25岁以下人群因糖尿病(1型和2型合并)死亡16300人,其中73.7%被归类为1型糖尿病。年龄标准化死亡率为每10万人口0.50,其中15900发生在中低SDI国家。在高SDI五分位数中,每10万人口的患病率为0.13;在低SDI五分位数中,每10万人口的患病率为0.60;在低SDI五分位数中,每10万人口的患病率为0.71。在SDI五分位数中,各国的发病率差异很大,部分原因是UHC的程度。

1990-2019年25岁以下1型糖尿病(A)和2型糖尿病(B)年龄标准化死亡率趋势(按SDI五分位数划分)

从1990年到2019年,全球所有糖尿病的年龄标准化死亡率下降了17.0%,而仅考虑1型糖尿病的年龄标准化死亡率下降了21.0%。然而,低SDI五分位数对所有糖尿病和1型糖尿病的下降率最低。

降低25岁以下的糖尿病死亡率仍然是一个重要挑战,尤其是在低和中低SDI国家。糖尿病的诊断和治疗不足可能是这些早期死亡的主要原因,这突出表明迫切需要提供更好的胰岛素和基础糖尿病教育和护理。这一死亡率指标来源GBD数据,有助于在全球范围内监测糖尿病相关死亡,与联合国的可持续发展目标保持一致,并作为各国1型和2型糖尿病基本糖尿病护理的指标。

参考文献:Diabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019 GBD 2019 Diabetes Mortality Collaborators † Show footnotes Open AccessPublished:February 07, 2022DOI:https://doi.org/10.1016/S2213-8587(21)00349-1

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    2022-12-17 howi
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    2022-02-11 小白努力长高高

    好文章,学习到了,谢谢。

    0

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