Diabetes Care:2型糖尿病患者对起搏器治疗的需求增加

2020-09-05 MedSci原创 MedSci原创

2型糖尿病患者对PM治疗的需求高于以匹配人群为基础的对照组。年龄、糖尿病病程和HbA1c似乎是PM治疗的危险因素。

2型糖尿病患者患血管疾病(包括心律不齐)的风险增加。在当代患者人群中,关于缓慢性心律失常的患病率以及后来使用起搏器(PM)进行治疗的需求研究较少。近日,糖尿病领域权威杂志Diabetes Care上发表了一篇研究文章,该研究旨在探讨1)与没有糖尿病的年龄和性别匹配的对照人群相比,2型糖尿病患者对PM植入的需求是否增加; 2)PM需求增加相关的患者特征。

在这项人群匹配的登记研究中,从1998年1月1日至2012年12月31日之间,总共416247名瑞典国家糖尿病登记处的2型糖尿病患者和2081235名年龄和性别匹配的对照者被纳入研究。随访至2013年12月31日,平均随访时间为7年。研究人员进行了Cox比例风险回归分析,以估计PM治疗的需求以及确定具有此类需求的患者特征。

2型糖尿病与PM治疗的需求增加相关(风险比为1.65 [95%CI为1.60-1.69];P<0.0001),在调整年龄、性别、教育水平、婚姻状况、出生国家和冠心病后仍持续(1.56 [1.51-1.60];P<0.0001)。接受PM治疗的危险因素包括年龄增长、HbA1c、BMI、糖尿病病程以及降血脂和降血压药物。

由此可见,2型糖尿病患者对PM治疗的需求高于以匹配人群为基础的对照组。年龄、糖尿病病程和HbA1c似乎是PM治疗的危险因素。

原始出处:

Elina Rautio,et al.Patients With Type 2 Diabetes Have an Increased Demand for Pacemaker Treatment: A Comparison With Age- and Sex-Matched Control Subjects From the General Population.Diabetes Care.2020.https://care.diabetesjournals.org/content/early/2020/09/02/dc20-0084

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    2020-09-07 HNYYM
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    2020-09-05 misszhang

    谢谢MedSci提供最新的资讯

    0

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