Otolaryngol Head Neck Surg:突发感音神经性听力损失与他汀类药物使用史之间的关系

2020-12-10 AlexYang MedSci原创

他汀类药物对突发感音神经性听力损失(SSNHL)的影响仍不清楚。最近,有研究人员调查了先前使用他汀与SSNHL之间的相关性。

他汀类药物对突发感音神经性听力损失(SSNHL)的影响仍不清楚。最近,有研究人员调查了先前使用他汀与SSNHL之间的相关性。

研究是一个嵌套的病例对照研究。研究包括了年龄≥40岁的参与者,共有5876名SSNHL患者与23504名对照,患者与对照在年龄、性别、收入和居住地区方面匹配。研究结果表明,与对照组相比,SSNHL组使用他汀类药物的时间更长(平均[SD],81.9[197.7]天vs 72.7[188.0]天;P=0.001)。然而,调整混杂因素后,他汀类药物的使用与SSNHL无关(调整后的OR,1.04;95%CI,0.98-1.11;P=0.245)。在原始模型中,他汀类药物的使用与SSNHL之间存在正相关(原始OR,1.10;95%CI,1.04-1.16;P=0.001)。然而,在所有亚组分析中,他汀类药物使用和SSNHL之间没有关联。

最后,研究人员指出,以前使用他汀类药物与SSNHL没有相关性。

原始出处:

So Young Kim , Jee Hye Wee , Chanyang Min et al. Association Between Sudden Sensorineural Hearing Loss and History of Statin Use: A Nested Case-Control Study. Otolaryngol Head Neck Surg. Nov 2020

 

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  5. [GetPortalCommentsPageByObjectIdResponse(id=2044169, encodeId=7e122044169cb, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Mon Mar 08 03:53:44 CST 2021, time=2021-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035474, encodeId=68c820354e447, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, 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level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sat Dec 12 14:53:44 CST 2020, time=2020-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907187, encodeId=46d190e187aa, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=04745411455, createdName=ms3000000546723755, createdTime=Fri Dec 11 22:51:33 CST 2020, time=2020-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=906998, encodeId=2ff090699890, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f8d05443443, createdName=ms8000002129192736, createdTime=Fri Dec 11 10:40:47 CST 2020, time=2020-12-11, status=1, ipAttribution=)]
    2020-12-14 刘煜

    阅读谢谢分享

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2044169, encodeId=7e122044169cb, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Mon Mar 08 03:53:44 CST 2021, time=2021-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035474, encodeId=68c820354e447, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, 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level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sat Dec 12 14:53:44 CST 2020, time=2020-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=907187, encodeId=46d190e187aa, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=04745411455, createdName=ms3000000546723755, createdTime=Fri Dec 11 22:51:33 CST 2020, time=2020-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=906998, encodeId=2ff090699890, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f8d05443443, createdName=ms8000002129192736, createdTime=Fri Dec 11 10:40:47 CST 2020, time=2020-12-11, status=1, ipAttribution=)]
    2020-12-13 ms3000000449926787

    哦,学习了!

    0

  7. 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authenticateStatus=null, createdAvatar=null, createdBy=f8d05443443, createdName=ms8000002129192736, createdTime=Fri Dec 11 10:40:47 CST 2020, time=2020-12-11, status=1, ipAttribution=)]
    2020-12-12 12346c4dm64暂无昵称

    他汀类药物的使用,在心血管疾病,很普及

    0

  8. 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  9. 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    2020-12-11 ms3000000546723755

    学习了

    0

  10. 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    2020-12-11 ms8000002129192736

    学习了

    0

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