J Periodontol: 锶功能化和氟化表面对早期骨整合作用的比较

2018-08-19 MedSci MedSci原创

研究表明,含有锶的医疗器械有助于骨愈合和骨整合。本研究的目的是评估表面功能化种植体(Ti-Sr-O)的体内性能,显示出可预测的锶释放特性,并将其与市售氟化物改性表面的性能进行比较。

研究表明,含有锶的医疗器械有助于骨愈合和骨整合。本研究的目的是评估表面功能化种植体(Ti-Sr-O)的体内性能,显示出可预测的锶释放特性,并将其与市售氟化物改性表面的性能进行比较。

方法:将Ti-Sr-O功能化,氟化改性,4级钛种植体植入成年雄性新西兰白兔的股骨髁中。用原子吸收光谱法(AAS)监测锶血清水平。植入后两周,使用限定的区域对骨-种植体接触(BIC%)和骨形成(BF%)进行组织形态学评估。

结果:BIC%的平均值显示出Ti-Sr-O和氟化物改性表面相当程度的骨整合度,而BF%显示BF增加与Ti-Sr-O的显着差异。 AAS测量未显示Ti-Sr-O修饰的种植体对锶血清浓度的任何影响。

结论:在该研究的限制内显示Ti-Sr-O涂层具有锶的持续释放特性,增强了骨的附着,因此可以在医学种植学领域内找到实际应用。

原始出处:

Vincent Offermanns, et al. Comparing the effect of strontium‐functionalized and fluoride‐modified surfaces on early osseointegration. Journal of Periodontology. 2018 August. doi:10.1002/JPER.17-0680

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    2019-04-13 feather89
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    2018-08-21 villahu
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    2018-08-20 lofter

    学习了感谢分享

    0

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    2018-08-19 happsf

    学习

    0

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    2018-08-19 医者仁心5538

    学习了

    0