Nature:重编程细胞同源移植也会发生排斥反应

2011-06-17 MedSci原创 MedSci原创

6月9日出版的自然杂志继5月刊发加州大学圣地亚哥分校的研究人员有关诱导多能干细胞(iPSCs)论文,再次刊登有关该研究的一篇快报,并予以评论,称研究人员在小鼠中证实将诱导多能干细胞(iPSCs)分化生成的多种组织移植至动物体内会产生快速的免疫排斥反应,即便iPSCs的起源细胞来自于移植小鼠本身。一直以来,大多数科学家们都认为来自于个人自身组织的重编程细胞能够被安全地移植到同一个体体内并能避免排斥反

6月9日出版的自然杂志继5月刊发加州大学圣地亚哥分校的研究人员有关诱导多能干细胞(iPSCs)论文,再次刊登有关该研究的一篇快报,并予以评论,称研究人员在小鼠中证实将诱导多能干细胞(iPSCs)分化生成的多种组织移植至动物体内会产生快速的免疫排斥反应,即便iPSCs的起源细胞来自于移植小鼠本身。一直以来,大多数科学家们都认为来自于个人自身组织的重编程细胞能够被安全地移植到同一个体体内并能避免排斥反应。这一研究结果或将对再生医学领域造成巨大的震动。

领导这一研究的是加州大学圣地亚哥分校的徐洋(Yang Xu)教授,其1989年毕业于武汉大学,之后赴美求学,获得哈佛大学的博士学位,并在麻省理工学院完成博士后的研究工作,目前任加州大学圣地亚哥分校生物系终身正教

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    2012-02-26 hb2008ye
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    2011-06-19 仁医06
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