Sci Rep: 贫血可增加脑卒中患者死亡的风险

2016-06-17 MedSci MedSci原创

贫血对脑卒中患者预后的影响仍不一致。研究者进行了一项队列研究的荟萃分析，评估有无贫血的卒中患者的死亡风险。系统的搜索PubMed，中国国家知识基础设施工程，web of science 和万方数据库，以确定从数据库开始到2015年11月的相关研究。汇集估计比值比与95%CI。进行亚组分析和敏感性分析。研究者用Begg's漏斗图和Egger测试来检测潜在的发表偏倚。这项荟萃分析包括十三个队列研究，共

贫血对脑卒中患者预后的影响仍不一致。研究者进行了一项队列研究的荟萃分析，评估有无贫血的卒中患者的死亡风险。

系统的搜索PubMed，CNKI，web of science 和万方数据库，以确定从数据库开始到2015年11月的相关研究。汇集估计比值比与95%CI。进行亚组分析和敏感性分析。研究者用Begg's漏斗图和Egger测试来检测潜在的发表偏倚。

这项荟萃分析包括十三个队列研究，共有19239例脑卒中患者。异质性研究（I（2） = 59%，P = 0.031 ）。随机效应模型的结果表明，贫血与脑卒中患者死亡风险增加相关（校正OR = 1.39，95%CI：1.22-1.58，P＜0.001 ）。亚组分析与总结果一致。

这项13个队列荟萃分析研究发现，贫血增加卒中患者的死亡风险。未来应进行更长随访的研究，证实这一发现，并探讨其可能的机制。

原始出处：

Li Z, Zhou T, et al. Anemia increases the mortality risk in patients with stroke: A meta-analysis of cohort studies. Sci Rep. 2016 May 23.

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2017-04-29 wangyang7969

#卒中患者#

23 0
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2017-01-26 weihongyv

#脑卒中患者#

31 0
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2016-10-12 ylzr123

好文，值得推荐。

61 0
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2017-04-26 sunylz

#患者死亡#

25 0
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2016-06-23 微分

学习了，加油

154 0
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2016-06-18 沉心多思

好文章，值得学习

54 0

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