Lancet:产前3D-MRI用于胎儿先天性心脏病的诊断

2019-04-21 MedSci MedSci原创

研究认为,利用图像处理软件进行标准胎儿MRI,所形成的血管高分辨率3D成像可提高胎儿先天性心脏病诊断的准确性

二维(2D)超声心动图是产前诊断先天性心脏病的主要手段,但在特殊情况下其精密度不足。胎儿核磁共振(MRI)成像非常容易受到胎儿运动的影响。近日研究人员探讨产前MRI与新型运动校正三维图像软件结合,作为胎儿超声心动图先天性心脏病的辅助手段的效果。

已知或怀疑先天性心脏病胎儿孕妇参与研究,对85个胎儿进行MRI数据采集,与2D图像重叠叠加,通过特定图像处理方法生成胎儿胸腔的超分辨率3D图像。将数据收集后,将配对的2D超声、超分辨率3D数据以及同期存档的临床胎儿MRI报告进行评估,并与产后结果进行比较。

MRI检查时平均胎龄为32周(24~36周),85例均获得高分辨率(0.50-0.75 mm)胎儿胸部三维数据集。血管测量结果与二维超声心动图的结果一致的有51例(组内相关系数为0.78),3D MRI对胎儿血管结构的显示效果优于未校正的2D MRI(680个解剖区域中,3D为657[97%]个区域,2D为358[53%]个区域)。分析2D和3D数据结构时(N=358), 321例(90%)的3D数据给出了更高的诊断质量分数, 37例(10%)与2D数据持平,无低于2D数据的分数。另外10例患者还描述了其他的解剖学特征,这些特征均在出生后得到证实。

研究认为,利用图像处理软件进行标准胎儿MRI,所形成的血管高分辨率3D成像可提高胎儿先天性心脏病诊断的准确性。

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    2020-02-25 howi
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    2019-04-23 145b036cm10暂无昵称

    普通彩超的漏诊率是多少?

    0

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    2019-04-23 huirong
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    2019-04-23 qilu_qi

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