Hepatology:美国参加私人保险人员的酒精性肝硬化的流行率、卫生保健状况和治疗成本

2018-09-24 MedSci MedSci原创

在一个具有全国代表性的参加私人保险人群中,AC注册者病情严重得多,重新入院的次数更多,而且与非酒精性肝硬化患者相比,酒精性肝硬化患者的医疗费用几乎翻了一倍。

研究背景:在美国,酒精性肝硬化(AC)是肝脏相关发病率和死亡率的主要原因。酒精使用的增多可能会导致更多的酒精性肝病。本研究旨在探究美国参加私人保险人员的酒精性肝硬化的流行率、卫生保健状况和治疗成本。

研究方法:研究搜集了年龄在18-64岁患者的AC数据,这些数据来自Truven marketo商业索赔和Encounters 数据库。研究确定了每年的流行率,并将其加权到国家雇主资助的私人保险人群。采用竞争风险分析,估计门脉高压并发症的发生率,并估计AC与成本之间的联系以及入院和再入院的关系。

研究结果:在2015年,294215例患者存在肝硬化,105871例患者存在AC。AC诊断时,患者平均年龄为53.5 岁,32%的患者为男性。在过去的7年里,预计全国肝硬化患病率从0.19%上升到0.27%(P<0.001),而AC患病率从0.07%上升到0.10%(P<0.001)。与非AC注册者相比,AC注册者在诊断时更有可能出现门静脉高压并发症,并有更高的年度肝硬化和与酒精相关的入院治疗(25例过量饮酒导致的肝硬化入院和6.3例过量饮酒相关的入院治疗)和各种病因诱导的再住院。AC患者诊断后第一年的人均花费几乎为非AC患者的2倍 (US$ 44,835 versus 23,319)。

研究结论:在一个具有全国代表性的参加私人保险人群中,AC注册者病情严重得多,重新入院的次数更多,而且与非酒精性肝硬化患者相比,酒精性肝硬化患者的医疗费用几乎翻了一倍。

原始出处


Mellinger JL, Shedden K, Winder GS, et al. The high burden of alcoholic cirrhosis in privately insured persons in the United States .Hepatology, 2018, 68(3), 872-882.

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beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Wed Sep 26 06:06:00 CST 2018, time=2018-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599578, encodeId=935515995e816, content=<a href='/topic/show?id=31992e25482' target=_blank style='color:#2F92EE;'>#保险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27254, encryptionId=31992e25482, topicName=保险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=db9918732976, createdName=feifers, createdTime=Wed Sep 26 06:06:00 CST 2018, time=2018-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046342, encodeId=438b10463424d, content=谢谢!最新的信息读起来就是收获大, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Mon Sep 24 18:06:00 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346455, encodeId=f8ed3464550d, content=qishi手gt, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63f91728829, createdName=您好呀, createdTime=Mon Sep 24 15:53:13 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346444, encodeId=df4234644481, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Sep 24 15:22:37 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2019-05-09 lixiaol
  5. 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  6. [GetPortalCommentsPageByObjectIdResponse(id=1771651, encodeId=330d1e71651c6, content=<a href='/topic/show?id=1d503660007' target=_blank style='color:#2F92EE;'>#卫生保健#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36600, encryptionId=1d503660007, topicName=卫生保健)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=054b38331488, createdName=minlingfeng, createdTime=Sun May 19 22:06:00 CST 2019, time=2019-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2041619, encodeId=ea502041619e7, content=<a href='/topic/show?id=618364624db' target=_blank style='color:#2F92EE;'>#治疗成本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64624, encryptionId=618364624db, topicName=治疗成本)], attachment=null, authenticateStatus=null, createdAvatar=, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Sep 24 15:22:37 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-26 gwc384
  7. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Sep 24 15:22:37 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-26 feifers
  8. 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encodeId=438b10463424d, content=谢谢!最新的信息读起来就是收获大, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Mon Sep 24 18:06:00 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346455, encodeId=f8ed3464550d, content=qishi手gt, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63f91728829, createdName=您好呀, createdTime=Mon Sep 24 15:53:13 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346444, encodeId=df4234644481, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Sep 24 15:22:37 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-24 guging

    谢谢!最新的信息读起来就是收获大

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1771651, encodeId=330d1e71651c6, content=<a href='/topic/show?id=1d503660007' target=_blank style='color:#2F92EE;'>#卫生保健#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36600, encryptionId=1d503660007, topicName=卫生保健)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=054b38331488, createdName=minlingfeng, createdTime=Sun May 19 22:06:00 CST 2019, time=2019-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2041619, encodeId=ea502041619e7, content=<a href='/topic/show?id=618364624db' target=_blank style='color:#2F92EE;'>#治疗成本#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64624, encryptionId=618364624db, topicName=治疗成本)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Sun May 12 20:06:00 CST 2019, time=2019-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2026344, encodeId=fe302026344e6, content=<a href='/topic/show?id=7dbd95485d2' target=_blank style='color:#2F92EE;'>#酒精性肝硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95485, encryptionId=7dbd95485d2, topicName=酒精性肝硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Wed Dec 05 23:06:00 CST 2018, time=2018-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720738, encodeId=a26a1e20738e5, content=<a href='/topic/show?id=a7ff65385f1' target=_blank style='color:#2F92EE;'>#流行率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=6851, encryptionId=221d685172, topicName=EPA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9b4077760, createdName=gwc384, createdTime=Wed Sep 26 06:06:00 CST 2018, time=2018-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1599578, encodeId=935515995e816, content=<a href='/topic/show?id=31992e25482' target=_blank style='color:#2F92EE;'>#保险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27254, encryptionId=31992e25482, topicName=保险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=db9918732976, createdName=feifers, createdTime=Wed Sep 26 06:06:00 CST 2018, time=2018-09-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046342, encodeId=438b10463424d, content=谢谢!最新的信息读起来就是收获大, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=guging, createdTime=Mon Sep 24 18:06:00 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346455, encodeId=f8ed3464550d, content=qishi手gt, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63f91728829, createdName=您好呀, createdTime=Mon Sep 24 15:53:13 CST 2018, time=2018-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=346444, encodeId=df4234644481, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Sep 24 15:22:37 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-24 您好呀

    qishi手gt

    0

  10. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Mon Sep 24 15:22:37 CST 2018, time=2018-09-24, status=1, ipAttribution=)]
    2018-09-24 医者仁心5538

    学习了

    0