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常用镇静镇痛药配制及使用：ICU手记

2016-12-11 李宏亮 北京大学第三医院 危重医学科 医学界急诊与重症频道

镇静镇痛药
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ICU内常用镇静镇痛药物配制及使用方法注：加粗字体为注意事项，因为可引起严重的血压下降。★ 咪唑安定清除半衰期：3 - 5 h起效时间：2 - 5 min建议剂量：1-2 mg，单次静推 0.5 - 10 mg/h 泵入常用配制方法（终浓度）：XX mg/XX ml （1 mg/ml）60kg 患者对应输注速度：0.5 - 10 ml/h★ 丙泊酚清除半衰期：20 - 30 h起效时间：90 s建


ICU内常用镇静镇痛药物配制及使用方法


注：加粗字体为注意事项，因为可引起严重的血压下降。


★ 咪唑安定


清除半衰期：3 - 5 h


起效时间：2 - 5 min


建议剂量：1-2 mg，单次静推 0.5 - 10 mg/h 泵入


常用配制方法（终浓度）：XX mg/XX ml （1 mg/ml）


60kg 患者对应输注速度：0.5 - 10 ml/h


★ 丙泊酚


清除半衰期：20 - 30 h


起效时间：90 s


建议剂量：不建议单次静推，25-100 ug/kg/min泵入


常用配制方法（终浓度）：1% 剂型 （10 mg/ml）


60kg 患者对应输注速度：9 - 36 ml/h


★ 右美托咪啶


清除半衰期：2 h


起效时间：1 - 2 min


建议剂量：不建议单次静推，负荷剂量 1.0  ug/kg（＞65 岁 0.5 ug/kg），超过 10 min 0.2-1.0 ug /kg/h 泵入维持


常用配制方法（终浓度）：200ug / 50ml （4 ug/ml）


60kg 患者对应输注速度：3 - 15 ml/h


★ 氟哌啶醇 （谵妄一线用药）


清除半衰期：10 - 24 h


起效时间：3 - 20 min


建议剂量：2-10 mg，bolus 2-10 mg/h泵入


★ 吗啡


清除半衰期：2 - 4 h


起效时间：30 min


建议剂量：1 - 4 mg，bolus 1 - 10 mg/h infusion


常用配制方法（终浓度）：XX mg/ XX ml （1 mg/ml）


60kg 患者对应输注速度：1 - 10 ml/h


★ 芬太尼


清除半衰期：2 - 5h


起效时间：4 min


建议剂量：25-100 ug，bolus 25 - 200 ug/h 泵入


常用配制方法（终浓度）：0.4 mg / 40 ml（10 ug/ml）


60kg 患者对应输注速度：2.5 - 20 ml/h


★ 布托啡诺


建议剂量：0.5 - 2 mg/Q4h


常用配制方法（终浓度）：5 mg / 50 ml（0.1 mg/ml）


60kg 患者对应输注速度：1.2 - 5 ml/h


Richmond躁动镇静量表

Richmond Agitation-Sedation Scale (RASS)


注：加粗字体为理想镇静深度

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1355222, encodeId=4ea51355222fa, content=<a href='/topic/show?id=256a96e9990' target=_blank style='color:#2F92EE;'>#镇痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96799, encryptionId=256a96e9990, topicName=镇痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579719, encodeId=20d615e97192b, content=<a href='/topic/show?id=567c96806cc' target=_blank style='color:#2F92EE;'>#镇痛药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96806, encryptionId=567c96806cc, topicName=镇痛药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef4d16558274, createdName=ms9476844295372110, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162016, encodeId=1ea716201620, content=很实用，感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f4b1993657, createdName=1e1aecabm93(暂无匿称), createdTime=Sun Dec 11 22:03:46 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161997, encodeId=bb3c16199eef, content=谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 18:34:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161987, encodeId=057b16198ed8, content=超级实用………, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 15:53:07 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161985, encodeId=740316198574, content=谢谢分享，学习了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sun Dec 11 14:50:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161981, encodeId=aa7c16198195, content=存到, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc2f1741513, createdName=1df0dffdm93(暂无匿称), createdTime=Sun Dec 11 14:24:34 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-13 zhaojie88

    #镇痛#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1355222, encodeId=4ea51355222fa, content=<a href='/topic/show?id=256a96e9990' target=_blank style='color:#2F92EE;'>#镇痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96799, encryptionId=256a96e9990, topicName=镇痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579719, encodeId=20d615e97192b, content=<a href='/topic/show?id=567c96806cc' target=_blank style='color:#2F92EE;'>#镇痛药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96806, encryptionId=567c96806cc, topicName=镇痛药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef4d16558274, createdName=ms9476844295372110, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162016, encodeId=1ea716201620, content=很实用，感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f4b1993657, createdName=1e1aecabm93(暂无匿称), createdTime=Sun Dec 11 22:03:46 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161997, encodeId=bb3c16199eef, content=谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 18:34:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161987, encodeId=057b16198ed8, content=超级实用………, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 15:53:07 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161985, encodeId=740316198574, content=谢谢分享，学习了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sun Dec 11 14:50:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161981, encodeId=aa7c16198195, content=存到, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc2f1741513, createdName=1df0dffdm93(暂无匿称), createdTime=Sun Dec 11 14:24:34 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-13 ms9476844295372110

    #镇痛药#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1355222, encodeId=4ea51355222fa, content=<a href='/topic/show?id=256a96e9990' target=_blank style='color:#2F92EE;'>#镇痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96799, encryptionId=256a96e9990, topicName=镇痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579719, encodeId=20d615e97192b, content=<a href='/topic/show?id=567c96806cc' target=_blank style='color:#2F92EE;'>#镇痛药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96806, encryptionId=567c96806cc, topicName=镇痛药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef4d16558274, createdName=ms9476844295372110, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162016, encodeId=1ea716201620, content=很实用，感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f4b1993657, createdName=1e1aecabm93(暂无匿称), createdTime=Sun Dec 11 22:03:46 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161997, encodeId=bb3c16199eef, content=谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 18:34:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161987, encodeId=057b16198ed8, content=超级实用………, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 15:53:07 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161985, encodeId=740316198574, content=谢谢分享，学习了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sun Dec 11 14:50:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161981, encodeId=aa7c16198195, content=存到, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc2f1741513, createdName=1df0dffdm93(暂无匿称), createdTime=Sun Dec 11 14:24:34 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-11 1e1aecabm93(暂无匿称)

    很实用，感谢

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1355222, encodeId=4ea51355222fa, content=<a href='/topic/show?id=256a96e9990' target=_blank style='color:#2F92EE;'>#镇痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96799, encryptionId=256a96e9990, topicName=镇痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579719, encodeId=20d615e97192b, content=<a href='/topic/show?id=567c96806cc' target=_blank style='color:#2F92EE;'>#镇痛药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96806, encryptionId=567c96806cc, topicName=镇痛药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef4d16558274, createdName=ms9476844295372110, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162016, encodeId=1ea716201620, content=很实用，感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f4b1993657, createdName=1e1aecabm93(暂无匿称), createdTime=Sun Dec 11 22:03:46 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161997, encodeId=bb3c16199eef, content=谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 18:34:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161987, encodeId=057b16198ed8, content=超级实用………, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 15:53:07 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161985, encodeId=740316198574, content=谢谢分享，学习了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sun Dec 11 14:50:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161981, encodeId=aa7c16198195, content=存到, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc2f1741513, createdName=1df0dffdm93(暂无匿称), createdTime=Sun Dec 11 14:24:34 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-11 为了宝宝

    谢谢分享！

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1355222, encodeId=4ea51355222fa, content=<a href='/topic/show?id=256a96e9990' target=_blank style='color:#2F92EE;'>#镇痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96799, encryptionId=256a96e9990, topicName=镇痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579719, encodeId=20d615e97192b, content=<a href='/topic/show?id=567c96806cc' target=_blank style='color:#2F92EE;'>#镇痛药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96806, encryptionId=567c96806cc, topicName=镇痛药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef4d16558274, createdName=ms9476844295372110, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162016, encodeId=1ea716201620, content=很实用，感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f4b1993657, createdName=1e1aecabm93(暂无匿称), createdTime=Sun Dec 11 22:03:46 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161997, encodeId=bb3c16199eef, content=谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 18:34:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161987, encodeId=057b16198ed8, content=超级实用………, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 15:53:07 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161985, encodeId=740316198574, content=谢谢分享，学习了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sun Dec 11 14:50:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161981, encodeId=aa7c16198195, content=存到, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc2f1741513, createdName=1df0dffdm93(暂无匿称), createdTime=Sun Dec 11 14:24:34 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-11 为了宝宝

    超级实用………

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1355222, encodeId=4ea51355222fa, content=<a href='/topic/show?id=256a96e9990' target=_blank style='color:#2F92EE;'>#镇痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96799, encryptionId=256a96e9990, topicName=镇痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579719, encodeId=20d615e97192b, content=<a href='/topic/show?id=567c96806cc' target=_blank style='color:#2F92EE;'>#镇痛药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96806, encryptionId=567c96806cc, topicName=镇痛药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef4d16558274, createdName=ms9476844295372110, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162016, encodeId=1ea716201620, content=很实用，感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f4b1993657, createdName=1e1aecabm93(暂无匿称), createdTime=Sun Dec 11 22:03:46 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161997, encodeId=bb3c16199eef, content=谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 18:34:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161987, encodeId=057b16198ed8, content=超级实用………, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 15:53:07 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161985, encodeId=740316198574, content=谢谢分享，学习了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sun Dec 11 14:50:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161981, encodeId=aa7c16198195, content=存到, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc2f1741513, createdName=1df0dffdm93(暂无匿称), createdTime=Sun Dec 11 14:24:34 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-11 ren1mw

    谢谢分享，学习了！

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1355222, encodeId=4ea51355222fa, content=<a href='/topic/show?id=256a96e9990' target=_blank style='color:#2F92EE;'>#镇痛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96799, encryptionId=256a96e9990, topicName=镇痛)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579719, encodeId=20d615e97192b, content=<a href='/topic/show?id=567c96806cc' target=_blank style='color:#2F92EE;'>#镇痛药#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=96806, encryptionId=567c96806cc, topicName=镇痛药)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ef4d16558274, createdName=ms9476844295372110, createdTime=Tue Dec 13 04:59:00 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162016, encodeId=1ea716201620, content=很实用，感谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f4b1993657, createdName=1e1aecabm93(暂无匿称), createdTime=Sun Dec 11 22:03:46 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161997, encodeId=bb3c16199eef, content=谢谢分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 18:34:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161987, encodeId=057b16198ed8, content=超级实用………, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161128/IMG583C2801690655672.jpg, createdBy=8d5d1986050, createdName=为了宝宝, createdTime=Sun Dec 11 15:53:07 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161985, encodeId=740316198574, content=谢谢分享，学习了！, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sun Dec 11 14:50:28 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161981, encodeId=aa7c16198195, content=存到, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=dc2f1741513, createdName=1df0dffdm93(暂无匿称), createdTime=Sun Dec 11 14:24:34 CST 2016, time=2016-12-11, status=1, ipAttribution=)]
    2016-12-11 1df0dffdm93(暂无匿称)

    存到

    0