ANN SURG:手术医师年龄影响食管癌患者预后

2018-06-13 MedSci MedSci原创

随着年龄增加,手术医师的经验、生理和心理状态都会发生改变。有种假说认为患者生存期随着手术医师年龄增加而延长,到达一定年龄后则开始下降。ANN SURG近期发表了一篇文章,验证这一问题。

随着年龄增加,手术医师的经验、生理和心理状态都会发生改变。有种假说认为患者生存期随着手术医师年龄增加而延长,到达一定年龄后则开始下降。ANN SURG近期发表了一篇文章,验证这一问题。

作者分析了1987年至2010年间在瑞典接受食管切除术的食管癌患者,随访至2016年。通过RA-CUSUM评估手术医师年龄与90天死亡率,全因死亡率,疾病特异性5年死亡率之间的关系。RA-CUSUM发现的年龄拐点在Cox回归模型中调整年龄,性别,合并症,肿瘤分期,肿瘤病理,新辅助治疗,时间等因素后再次进行分析。研究结果表明,在139名外科医生实施额1761例食管切除术中,RA-CUSUM分析的90天死亡率拐点在43岁和56岁。全因死亡率和疾病特异性5年死亡率的拐点均在52岁和56岁。与52到55岁的手术医师相比,手术医师年龄≤51岁与90天死亡率和全因死亡率增加有关。手术医师年龄≥56岁时,90天死亡率,5年全因死亡率和疾病特异性5年死亡率均增加。

文章最后认为,手术医师年龄≤51岁和≥56岁可能会增加食管切除术后短期和长期死亡率。

原始出处:
Marker Sheraz R,MRCS MSc MA,et al. Surgeon Age in Relation to Prognosis After Esophageal Cancer Resection.ANN SURG.July 2018 doi:10.1097/SLA.000000000002260

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    2018-06-15 zhouqu_8
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    2018-06-13 Jackie Li

    学习

    0

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    2018-06-13 1ddf0692m34(暂无匿称)

    学习了.谢谢分享

    0

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