Clin Oral Investig:牙周炎患者半放线放线杆菌和牙龈卟啉单胞菌的抗菌敏感性

2018-07-10 lishiting MedSci原创

研究将牙周炎患者的半放线放线杆菌和牙龈卟啉单胞菌分离出来。它在龈下刮治生物膜术后的持续存留是导致较差临床疗效的原因。这篇研究的目的是为了检测阿莫西林,阿莫西林加克拉维酸盐,甲硝唑和阿奇霉素对半放线放线杆菌和牙龈卟啉单胞菌的抗菌特异性。另外,也比较存留在患者口内半放线放线杆菌和牙龈卟啉单胞菌的微生物模式。

研究将牙周炎患者的半放线放线杆菌和牙龈卟啉单胞菌分离出来。它在龈下刮治生物膜术后的持续存留是导致较差临床疗效的原因。这篇研究的目的是为了检测阿莫西林,阿莫西林加克拉维酸盐,甲硝唑和阿奇霉素对半放线放线杆菌和牙龈卟啉单胞菌的抗菌特异性。另外,也比较存留在患者口内半放线放线杆菌和牙龈卟啉单胞菌的微生物模式。研究纳入45名摩洛哥牙周炎患者,获取其龈下样本并进行培养。采用浊度法分离23株半放线放线杆菌和30株牙龈卟啉单胞菌克隆(54株),并分别施以阿莫西林,阿莫西林加克拉维酸盐,甲硝唑和阿奇霉素,以进行敏感性试验。计算机体对50 (MIC50)和90% (MIC90)的最小抑菌浓度。结果显示,半放线放线杆菌和牙龈卟啉单胞菌的检出率分别为79.5和84.4%。半放线放线杆菌对阿莫西林,阿莫西林加克拉维酸具有敏感性;然而,28%对阿奇霉素具有耐药性,61.7%对甲硝锉具有抵抗作用。没有发现牙龈卟啉单胞菌对阿莫西林,阿莫西林加克拉维酸盐,甲硝唑和阿奇霉素存有耐药性。结论:摩洛哥牙周炎患者半放线放线杆菌和牙龈卟啉单胞菌的检出率较高,仅半放线放线杆菌对阿奇霉素和甲硝锉具有抗菌耐药性。临床意义:在摩洛哥牙

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    2019-01-15 小几洁
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  6. [GetPortalCommentsPageByObjectIdResponse(id=2020446, encodeId=4d262020446b3, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Tue Jan 15 19:13:00 CST 2019, time=2019-01-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051182, encodeId=d66e20511827a, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Sat Sep 29 16:13:00 CST 2018, time=2018-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1330756, encodeId=7f9b1330e56be, content=<a href='/topic/show?id=c6b455688d1' target=_blank style='color:#2F92EE;'>#抗菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=55688, encryptionId=c6b455688d1, topicName=抗菌)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/2898B09F0DA89357D0D54A725E611AC7/100, createdBy=fdd32500040, createdName=ms7899726347904398, createdTime=Thu Jul 12 12:13:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361057, encodeId=829f136105e59, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6f7a159, createdName=3631173, createdTime=Thu Jul 12 12:13:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1388420, encodeId=41221388420be, content=<a href='/topic/show?id=7ef25e5346b' target=_blank style='color:#2F92EE;'>#敏感性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57534, encryptionId=7ef25e5346b, topicName=敏感性)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJnkE6UvGFfMS41qV0RicWvVTTeLMicqibeZH5GqO4YhNicyl1Y9jFhylIUBn9ntPYy9jhk5hrfic5cRYw/132, createdBy=5f822500020, createdName=ms5236388012055669, createdTime=Thu Jul 12 12:13:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450936, encodeId=eefd145093691, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=hb2008ye, createdTime=Thu Jul 12 12:13:00 CST 2018, time=2018-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330749, encodeId=ecec330e490e, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Wed Jul 11 05:51:55 CST 2018, time=2018-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=330693, encodeId=fc3233069330, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=82311653708, createdName=医者仁心5538, createdTime=Tue Jul 10 22:27:24 CST 2018, time=2018-07-10, status=1, ipAttribution=)]
    2018-07-12 hb2008ye
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    2018-07-11 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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    2018-07-10 医者仁心5538

    学习了

    0

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