Sci Rep:素食者和非素食者泌尿系统感染风险研究

2020-02-11 AlexYang MedSci原创

泌尿系统感染(UTI)主要是大肠杆菌通过肠道-粪便-尿道上行途径引起的。最近的研究发现引起UTIs的大肠杆菌株系(肠外致病大肠杆菌ExPEC)与肠道致病性菌株和正常的共生菌株不同。进一步的研究发现,包括家禽和猪肉的肉类是ExPECs的主要来源。素食主义者不吃肉,并且理论上应该更少的接触ExPEC。然而,目前还没有研究调查是否素食者的饮食能够减少UTI的风险。最近,有研究人员调查了素食者饮食与UTI

泌尿系统感染(UTI)主要是大肠杆菌通过肠道-粪便-尿道上行途径引起的。最近的研究发现引起UTIs的大肠杆菌株系(肠外致病大肠杆菌ExPEC)与肠道致病性菌株和正常的共生菌株不同。进一步的研究发现,包括家禽和猪肉的肉类是ExPECs的主要来源。素食主义者不吃肉,并且理论上应该更少的接触ExPEC。然而,目前还没有研究调查是否素食者的饮食能够减少UTI的风险。

最近,有研究人员调查了素食者饮食与UTI风险之间的相关性。研究人员在2005年到2014年前瞻性的调查了9724名无UTI的佛教人员。在10年的跟踪调查期间,661名人员发生UTI。研究人员通过食物频率问卷调查了饮食情况,并在调整了年龄、性别、教育水平、引用酒精、抽烟、高血压糖尿病、高血脂和诱发UTIs的疾病条件后,利用Cox回归分析评估了素食饮食与UTI风险的相关性。研究发现,整体上来讲素食饮食与风险降低16%相关(HR: 0.84, 95%CI: 0.71-0.99)。另外,亚群分析表明了素食饮食和UTI的保护性关系主要在女性(HR: 0.82, 95% CI: 0.69-0.99)、不抽烟(HR: 0.80, 95% CI: 0.67-0.95)和简单的UTI(HR: 0.81, 95% CI: 0.68-0.98)中发现。

原始出处:

Yen-Chang Chen, Chia-Chen Chang, Tina H. T. Chiu et al. The risk of urinary tract infection in vegetarians and non-vegetarians: a prospective study. Sci Rep. 30 Jan 2020

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    2020-02-14 土豆2995

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