NEJM:粟粒性结核-病例报道

2020-09-17 MedSci原创 MedSci原创

胸部X光片发现两个肺野中均分布着大小均一的结节,这一发现与粟粒性结核一致,痰液样本的抗酸杆菌涂片阳性。

患者为一名56岁的男子,因疲劳2个月,体重减轻10公斤,伴有盗汗和发热而到急诊就诊。他咳​嗽时咳出的痰偶尔会带血。他十年前从海地移民到美国。

经检查,体温为36.2°C。他呼吸舒适,但看上去虚胖。听诊时,两个肺部的气流量相等,没有裂纹声或喘息。眼底镜检查发现双眼后极多形黄色病变,边界不明显。胸部X光片发现两个肺野中均分布着大小均一的结节,这一发现与粟粒性结核一致。眼部检查结果与脉络膜结节一致。痰液样本的抗酸杆菌涂片阳性。

患者开始接受利福平、异烟肼、吡嗪酰胺和乙胺丁醇联合治疗。治疗1周后,重复痰标本检查发现耐酸杆菌涂片阴性。

6周后,从最初就诊时留取的痰液样本中培养出全敏结核分枝杆菌。开始治疗后,患者的症状得到改善,并且他完成了6个月的治疗。

原始出处:

Jerald Pelayo,et al.Miliary Tuberculosis.N Engl J Med 2020;https://www.nejm.org/doi/full/10.1056/NEJMicm2001934

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    2021-09-29 呼吸科小医生

    学习了,谢谢分享!

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1056260, encodeId=650110562605b, content=学习了,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210612/4cac76eb29134c3aa63a2560971ec878/648fa1cb22cd430380c051eb0a8f6259.jpg, createdBy=7a8d5519826, createdName=呼吸科小医生, createdTime=Wed Sep 29 20:57:51 CST 2021, time=2021-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=889332, encodeId=2e908893323e, content=典型的影像, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=98685277935, createdName=14838411m74暂无昵称, createdTime=Wed Sep 30 08:12:06 CST 2020, time=2020-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1254378, encodeId=be8612543e867, content=<a href='/topic/show?id=f30ae86297d' target=_blank style='color:#2F92EE;'>#结核#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78629, encryptionId=f30ae86297d, topicName=结核)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=huhuaidong387, createdTime=Fri Sep 18 23:16:08 CST 2020, time=2020-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1035417, encodeId=ce2e103541e87, content=顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=旺医, createdTime=Thu Sep 17 11:16:08 CST 2020, time=2020-09-17, status=1, ipAttribution=)]
    2020-09-30 14838411m74暂无昵称

    典型的影像

    0

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    2020-09-17 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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