CCLM:常规临床实验室对巨泌乳素的观察性研究

2018-08-01 MedSci MedSci原创

目前建议对所有具有升高催乳素的样品中是否存在巨乳酸进行检查。我们对巨泌乳素的经验进行了回顾性研究,以确定巨乳酸的发生率和自然史。

本研究是一项大型临床实验室对巨泌乳素进行的回顾性研究。对那些总催乳素> 1000mIU / L的切有必要检测的样品测量大量催乳素,使用Siemens Centaur测量催乳素,并在聚乙二醇(PEG)沉淀后测量巨乳酸。

结果显示:总催乳素> 1000 mIU / L的样品中大环内酯的发生率为36/6705.4%)。在此期间,收到了12,064个样本用于催乳素分析。在2006年以来的时期内,22名受试者的样本具有分离的巨泌乳素,在中位时间为0.46年后,另一个样本没有检测到巨泌乳素。二十五名受试者连续多次测量巨泌乳素,持续中位数为2.1年。14名受试者6个已经进行PEG沉淀的样品。在这些受试者中,PEG沉淀的中位数为6年的再现性为1.1CV(恢复75[26-110](中位数[范围]))。

巨泌乳素的存在可能会随着时间的推移而发生变化,我们无法对一旦进行了巨泌乳素血症的检测,如果后续样本是高催乳素血症则没有必要重复调查进行建议; 人们也不能认为即使先前被排除在外也不会发展为巨泌乳素。

原始出处:

Theresa Winter, Long-term stability of glucose: glycolysis inhibitor vs. gel barrier tubes

本文系梅斯医学(MedSci)原创编译整理,转载需授权!


版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1941558, encodeId=e9af194155890, content=<a href='/topic/show?id=108022e76b3' target=_blank style='color:#2F92EE;'>#临床实验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22776, encryptionId=108022e76b3, topicName=临床实验)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, createdName=liuhuangbo, createdTime=Sat Dec 01 22:55:00 CST 2018, time=2018-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2037102, encodeId=8440203e1023b, content=<a href='/topic/show?id=ba6264e5038' target=_blank style='color:#2F92EE;'>#泌乳素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64750, encryptionId=ba6264e5038, topicName=泌乳素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Wed Feb 13 15:55:00 CST 2019, time=2019-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1499816, encodeId=ed36149981620, content=<a href='/topic/show?id=113c90584e6' target=_blank style='color:#2F92EE;'>#观察性研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90584, encryptionId=113c90584e6, topicName=观察性研究)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=34519379140, createdName=shock_melon, createdTime=Thu Aug 02 23:55:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335551, encodeId=1341335551cc, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Aug 01 14:16:24 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335499, encodeId=45ba33549956, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Aug 01 09:46:52 CST 2018, time=2018-08-01, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1941558, encodeId=e9af194155890, content=<a href='/topic/show?id=108022e76b3' target=_blank style='color:#2F92EE;'>#临床实验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22776, encryptionId=108022e76b3, topicName=临床实验)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, createdName=liuhuangbo, createdTime=Sat Dec 01 22:55:00 CST 2018, time=2018-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2037102, encodeId=8440203e1023b, content=<a href='/topic/show?id=ba6264e5038' target=_blank style='color:#2F92EE;'>#泌乳素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64750, encryptionId=ba6264e5038, topicName=泌乳素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Wed Feb 13 15:55:00 CST 2019, time=2019-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1499816, encodeId=ed36149981620, content=<a href='/topic/show?id=113c90584e6' target=_blank style='color:#2F92EE;'>#观察性研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90584, encryptionId=113c90584e6, topicName=观察性研究)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=34519379140, createdName=shock_melon, createdTime=Thu Aug 02 23:55:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335551, encodeId=1341335551cc, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Aug 01 14:16:24 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335499, encodeId=45ba33549956, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Aug 01 09:46:52 CST 2018, time=2018-08-01, status=1, ipAttribution=)]
    2019-02-13 jktdtl
  3. [GetPortalCommentsPageByObjectIdResponse(id=1941558, encodeId=e9af194155890, content=<a href='/topic/show?id=108022e76b3' target=_blank style='color:#2F92EE;'>#临床实验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22776, encryptionId=108022e76b3, topicName=临床实验)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, createdName=liuhuangbo, createdTime=Sat Dec 01 22:55:00 CST 2018, time=2018-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2037102, encodeId=8440203e1023b, content=<a href='/topic/show?id=ba6264e5038' target=_blank style='color:#2F92EE;'>#泌乳素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64750, encryptionId=ba6264e5038, topicName=泌乳素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Wed Feb 13 15:55:00 CST 2019, time=2019-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1499816, encodeId=ed36149981620, content=<a href='/topic/show?id=113c90584e6' target=_blank style='color:#2F92EE;'>#观察性研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90584, encryptionId=113c90584e6, topicName=观察性研究)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=34519379140, createdName=shock_melon, createdTime=Thu Aug 02 23:55:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335551, encodeId=1341335551cc, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Aug 01 14:16:24 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335499, encodeId=45ba33549956, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Aug 01 09:46:52 CST 2018, time=2018-08-01, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1941558, encodeId=e9af194155890, content=<a href='/topic/show?id=108022e76b3' target=_blank style='color:#2F92EE;'>#临床实验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22776, encryptionId=108022e76b3, topicName=临床实验)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, createdName=liuhuangbo, createdTime=Sat Dec 01 22:55:00 CST 2018, time=2018-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2037102, encodeId=8440203e1023b, content=<a href='/topic/show?id=ba6264e5038' target=_blank style='color:#2F92EE;'>#泌乳素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64750, encryptionId=ba6264e5038, topicName=泌乳素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Wed Feb 13 15:55:00 CST 2019, time=2019-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1499816, encodeId=ed36149981620, content=<a href='/topic/show?id=113c90584e6' target=_blank style='color:#2F92EE;'>#观察性研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90584, encryptionId=113c90584e6, topicName=观察性研究)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=34519379140, createdName=shock_melon, createdTime=Thu Aug 02 23:55:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335551, encodeId=1341335551cc, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Aug 01 14:16:24 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335499, encodeId=45ba33549956, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Aug 01 09:46:52 CST 2018, time=2018-08-01, status=1, ipAttribution=)]
    2018-08-01 131****1460

    学习了受益匪浅

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1941558, encodeId=e9af194155890, content=<a href='/topic/show?id=108022e76b3' target=_blank style='color:#2F92EE;'>#临床实验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22776, encryptionId=108022e76b3, topicName=临床实验)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6779163, createdName=liuhuangbo, createdTime=Sat Dec 01 22:55:00 CST 2018, time=2018-12-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2037102, encodeId=8440203e1023b, content=<a href='/topic/show?id=ba6264e5038' target=_blank style='color:#2F92EE;'>#泌乳素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64750, encryptionId=ba6264e5038, topicName=泌乳素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Wed Feb 13 15:55:00 CST 2019, time=2019-02-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1499816, encodeId=ed36149981620, content=<a href='/topic/show?id=113c90584e6' target=_blank style='color:#2F92EE;'>#观察性研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90584, encryptionId=113c90584e6, topicName=观察性研究)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=34519379140, createdName=shock_melon, createdTime=Thu Aug 02 23:55:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335551, encodeId=1341335551cc, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Wed Aug 01 14:16:24 CST 2018, time=2018-08-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335499, encodeId=45ba33549956, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Wed Aug 01 09:46:52 CST 2018, time=2018-08-01, status=1, ipAttribution=)]
    2018-08-01 龙胆草

    学习谢谢分享

    0